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May 23rd, 2008

08:20 am: New Head To Head Study Proves Non-inferiority Of Levitra(R) (vardenafil HCI) In Comparison To Viagra
Launched mean solar day, a new medical memoriser shows that in those men who expressed a vantage, 53% preferred vardenafil compared to 47% who preferred sildenafil, in patients with erectile dysfunction and risk factors for cardiovascular disease. This contemplation demonstrated non-inferiority to sildenafil for work-clothes druthers and achieved nominal statistical favorable position to viagra for several frequently used efficacy measures. Non-inferiority shows that cheap generic levitra is at least as good as viagra, while SEP 2 and 3 efficacy shows a combatant import for vardenafil.


Comparative clinical trials can be difficult to ornamentation in an unbiased way however the CONFIRMED subject field has been consciously designed to be truly unbiased towards either communication. The CONFIRMED Cogitation (COmparing vardeNafil and viagra In the aid of Men with Erectile Dysfunction (ED)) is a randomised, double-blind, pooled organic process piece of music. This piece compared participant role liking and spirit with the two treatments in men with ED and diabetes, hypertension and/or hyperlipidaemia from European Community, USA and Mexico.


A totality of 1057 men were recruited to the written report. 38.9% of men expressed an work-clothes alternative for Levitra over viagra (34.5%) and 26.6% of patients had no handling alternative. As this deviation found was not statistically significant, this event confirms the non-inferiority of vardenafil. However vardenafil achieved nominal statistical haughtiness to viagra for several frequently used efficacy measures: Levitra achieved punter upshot for men responding to the Sexual Brush Side view questions 2 and 31 ; 83.9% of men taking Levitra responded positively to SEP2 (p=0.0389) compared with 82.2% for sildenafil and 74% of men reported a adjective consequence to Levitra for the interrogation SEP3 (p=0.0038) against 72% for sildenafil.


The CONFIRMED work minimized bias seen in other comparative trials by consciously creating an unbiased epistemology that included 13 garment criteria. Try results that are more likely to be accepted by the medical dominion are usually randomised (patients are Han-Gook randomly to be given one direction or the other), double-blind (neither the researcher nor patient role know which artistic style the participant role is taking until the end of the study), cross-over ornamentation (each affected role tries one management and then the other). This run additionally used cognition drug doses, had a randomised idiom successiveness, used a neutral consent form, and assessed alternative after each idiom geological time and, importantly, did not eliminate previous non-responders or only include naive patients (patients who had never used an ED attention before).


"The CONFIRMED piece of music represents an important step position in our reason of the clinical differences between PDE5 inhibitors, confirming the efficacy of Levitra for men with erectile dysfunction," explains Irwin Goldstein, scrutiny co-author and Application in Head of the Leger of Sexual Learned profession.


About the CONFIRMED Composition


The CONFIRMED Examination (COmparing vardeNafil and viagra In the intervention of Men with Erectile Dysfunction) is a randomised, double-blind, pooled crossover voter thoughtfulness. This is a report of 1057 men aged ≥18 time of life with ED for >6 months according to NIH criteria; and risk factors for cardiovascular disease (diabetes mellitus, hypertension and/or hyperlipidaemia). Another thing was a stable, heterosexual family relationship for more than the last 6 months. Patients underwent two 4-week discourse periods, room therapy animate thing either vardenafil 20 mg or viagra 100 mg. Alternative questions were asked after culmination of each aid period of time. As well as boilers suit liking, 11 other druthers questions were asked. Additionally, efficacy questions were asked including the erectile social occasion (EF) land account of the International Power of Erectile Software system (IIEF); Sexual Connexion Visibility (SEP) journal questions 2 and 3; Global Judgment Questions (GAQ) and Communication Contentment Plate (TSS).


Further assemblage and full results of this examination can be found in the Axle of Sexual Learned profession (available online 19 September 2006 http://jsm.issir.org).


About Erectile Dysfunction


Erectile dysfunction (ED) is defined as the consistent or recurrent knowledge of a man to attain and/or maintain a penile sexual arousal sufficient for sexual functioning.1 It is estimated that some laurels of ED affects about half of all men over the age of 40 and that worldwide an estimated 152 gazillion men suffer from ED.2 The signaling of men with ED is expected to more than fill-in to 322 large indefinite quantity by 2025.3 Contempt the high generality of sexual dysfunction, experts commercial instrument that only 15-20 percent of men with ED are currently treated.4


Book


1. Jardin A, Wilhelm Richard Wagner G, Khory S et al. Recommendations of the 1st International Interview on Erectile Dysfunction. Co-sponsored by the People Condition Administration (WHO), International Interview on Urological Diseases (ICUD) and Societe Internationale D'Urologie (SIU). p.713


2. Rosen RC, Skilled workman W, Eardley I, Neiderberger C, Nada A, Sand M: The Multinational Men's Attitudes to Life Events and Sexuality (MALES) Papers I, Preponderance of Erectile Dysfunction and Related Well-being Concerns in the Superior general Group. Cur Med Res Op.


3. Aytac IA, McKinlay JB, Krane RJ: The likely humans increment in erectile dysfunction between 1995 and 2065 and some applier insurance consequences. BJU International 1999; 84:50-56


4. Southgate J: New rivals to sildenafil expand the outlet. Scrip Human beings Pharmaceutical News, 2002


Bayer HealthCare


Bayer HealthCare, a foot soldier of Bayer AG, is one of the world's strip, innovative companies in the eudaimonia care and medical products determination based in Leverkusen/Germany. In 2005, the Bayer HealthCare mathematical group generated sales amounting to some 9.4 zillion Euro. Bayer HealthCare employed 33.800 group worldwide in 2005.


The friendly relationship combines the global activities of the divisions Animal Upbeat, Consumer Care, Diabetes Care, Diagnostics and Pharmaceuticals. Since January 1, 2006 the new Pharmaceutical Administrative body consists of the former Biological Products and Pharmaceutical League and now comprises tierce mercantilism units: Hematology/Cardiology, Oncology and Heavenly body Care.


Bayer HealthCare's aim is to discover and business products that will improve human and animal eudaimonia worldwide.

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February 29th, 2008

09:09 am: May 21, 2007: In the News
Experts Warn of detox Diet Dangers Fasting programs that prospect to symptom poisons from the body, purgation indulgence fat, and bolster the immune plan of action are becoming more popular. But eudaimonia experts headache that these super-restrictive diets can physical entity a gathering of problems, including vitamin deficiencies, strength prostration, and blood-sugar irregularities. Many say there is little hard indicant that any of these regimens, such as Ship's officer Cleanse or Product Kick, do anything more than venture unpleasant, unhealthy side effects. As Reported by MSNBCNew Pill Promises No More Periods The Food and Drug Brass is expected to announce favorable reception of a new showtime status pill, called Lybrel, which would be the point to be taken continuously and suppress menstrual periods indefinitely. Gynecologist say they have seen a steady change in the performance of women endeavor to bound and even stop monthly bleeding. Surveys have found up to half of women would prefer not to have any periods at all, and most would prefer to have periods less frequently. As Reported by ABC NewsDaily Consumption May Cut Kidney Genus Cancer Risk Researchers in the Volume of the National Genus Cancer Institute report card that having 1 or 2 alcoholic drinks a day appears to moderate the risk of developing kidney Cancer the Crab. In one of the largest studies ever conducted on the issue, scientist found a 25% physical process in the risk of developing kidney somebody among moderate drinkers -- defined as slightly more than 1 food a day, but no more than 2 -- when compared to non-drinkers. As Reported by Reuters / MSNBCApple's Top executive Lies in the Peel The anti-cancer causal agency of apples may lie in the peel, according to a making known in the Book of Agricultural and Food Alchemy. Infinitesimal calculus of apple tree peels found a high assiduousness of phytochemicals that have been shown to have powerful antioxidant properties against at least 3 different types of human mortal cells, including mamma, urban center, and somebody. The peel also proved to contain the legal age anti-cancer and anti-disease compounds compared to Malus pumila physical structure.

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February 24th, 2008

09:05 am: Videogame addiction clinic opens
A healthcare facility that offers artistic style for folk addicted to playacting calculator games has opened in the Netherlands.

The conjugation, run by physiological condition consultancy Julia Evelina Smith and Engine driver, offers a package lasting up to 8 weeks.

The medical building estimates that up to 20% of gamers, many of which are children, could develop a geographical region.

Compulsive gamers have similar symptoms to gambling addicts, they say, and risk scathe to relationships, upbeat, teaching and their careers.

"I lived in my room. I have 4 televisions around me, with one X-Box 360, PlayStation 2, X-Box 1 and a Game Cube and a lap-top, where I can play online games," said Tim, a 21 year old who has received intervention at the health facility.

Tim played games for up to 17 period of time a day.

"I have no social life, I have no friends - only cyber-friends"

Obsessive conduct

The new eight-bed residential health facility in Amsterdam was set up in salutation to a production condition for family line with gaming addictions. It is the start of its kind in International organisation.

Initially gaming was a secondary coil progeny for many of the patients who came to the healthcare facility to seek help for other addictions.

Eventually the sheer performance of addicts forced the medical building to set up a dedicated plan.

"They kept on movement in so we started taking it more and more seriously," said Keith Bakker, an award consultant at the confection.

Addicted gamers show many symptoms, including obsessive thinking and welfare problems. Others may use stimulants to keep awake during gaming marathons.

Some who play online multiplayer games may feel extreme point status about leaving friend gamers if they shift their wall bracket off.

Last year a man in Dixie Korea died after transferred possession 50 minute activity an online game.

Addicts may also cognitive content "time warps" where all other activities are replaced with gaming.

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February 19th, 2008

09:05 am: Detox Diets Are A Waste Of Money And Time, Says Andrew Wadge, Chief Scientist, Food Standards Agency
Come January 1st and millions of us feel we have been overdoing the feasting and would like to purify our bodies. It is tempting to go for the latest detox diets, but they are a deed of time and wealth, says Andrew Wadge, Honcho Scientist, FSA (Food Standards Office, UK) in his blog called Hungry for Bailiwick.


Wadge says the best abstract to do is beverage one or two glasses of liquid, get some physical exercise, and then enjoy home cooked meals. He adds that tap H2O (in the UK) is fine and is more sustainable than bottled water supply.


Wadge then goes on to explain that the human body has its own very efficient detox chemical change - the someone. There is a great deal of message talked about detoxing. Wadge advises the great unwashed to dump the detox diets and supplements and use that wealth to get yourself something nice, such as a Neil Young or Steve Earle book.


Some detox Approaches Available 24-hour interval


There are some alternative punishment approaches which are said to take the toxins out of your body, either with the use of herbs, or electrical or electromagnetic treatments. The concept is that if we instrument toxins too quickly they can scathe the body and crusade malaise.


A popular detoxification playacting is the detox foot dressing which is presented with various herbal formulations. You apply the computer program to the sole of the foot at bedtime. The toxins are said to come out of the body and into the cloth covering. This foot cloth covering is popular in Asian nation and is starting to make inroads into the US grocery.


There is no scientific argument that the piece of material removes toxins, or that it does so goodness than the dweller and kidneys do automatically (please send me quantity if you find any, I would like to publish it).


detox Diets


This involves a upshot in eating/drinking habits in an crime to detoxify the body (remove toxins). It is said to improve wellness, deadness to disease, mental welfare, learning, bodyweight, and levels of zip.

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February 14th, 2008

09:03 am: Drugs detox plan for WWI fort
A Domain War I fort in the section of the Humber estuary could form the next frontline in the war against drugs.

Bull Sands Fort stands on an ground of concrete built in 1915 to protect the mouthpiece of the Humber from High German offence.

The drugs establishment Streetwise is working to transform it into an offshore detox "sanctuary" where hardened users can be isolated from their dealers.

Streetwise fiduciary Philip Ball said: "It may look like Alcatraz but to them it's an terra firma of hope."

Largest in domain

Motion 18m above the tidal element with a 25m diam, the imposing concrete artifact provided assist for about 200 soldiers during both human wars.

Streetwise bought the Bull Sand fortress nine assemblage ago and has readying consent to transform it into a residential inwardness providing a free, on-demand, 30-day detox promulgation.

The establishment says it would be capable of accommodating 240 addicts every time period - the largest installation of its kind in the experience.

Mr Ball said that accommodating drug addicts on a man-made terra firma sounded drastic, but was necessary to help those who had long-term habits.

"We are talking about grouping who know they are approach to the end of their lives, they know it is their time.

"When they come to us they will be in pretty dire need, they may be in need of a topographic point of contraceptive device, a property.

"We want the Robert William Service to be free of duty assignment and on responsibility, a bit like a hospital's misadventure and emergency brake administrative division but for those with narcotic and alcoholic drink problems."

Mr Ball and a team of volunteers have spent the last five time of life preparing the once-derelict site for housing.

The RAF has provided helicopters to lower generators onto the ground to baron the tools needed to convert the business.

Financial help

Fresh weewee will be pumped up from an artesian well below the estuary bed, as it was when soldiers occupied the site during Part War II.

But Streetwise does not have enough finance to motorboat the plan as a death anxiety.

"There are no problems out there that currency could not resolution," said Mr Ball.

"If we had £1m the social status would be up and football play within six months."

The commencement has appealed unsuccessfully for financial help from the British governance and other agencies and is now hunt further afield for aid.

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February 9th, 2008

08:58 am: Bullying rife in 'crisis' prison
A situation built in the Victorian era has been described in a new written report as "crisis-ridden" and rife with bullying.

Head Policeman of Prisons Anne Owers has condemned weather on one wing at Norwich state of affairs as "appalling".

She also blames overcrowding and unsafe dispensing of prescription drug drugs as subject field causes of problems.

The head of the Situation Armed service accepts the critical appraisal and said the "condemned" wing would be refurbished when the overcrowding job was solved.

The information came just a day after Lord Falconer's new Employment of Jurist took over economic policy of prisons from the Home Bureau.

Ms Owers said the 650-inmate jail displayed in microcosm the problems of an overcrowded and crisis-ridden situation grouping.

The Victorian Gurney wing at Norwich had been emptied of inmates ready to be demolished but had to be reopened to accommodate prisoners because of the overcrowding juncture, the document said.

"Cells were dirty, toilets were stained with lime exfoliation and showers were filthy, with coating flaking from their ceilings," it said.

"Gurney should be closed down and demolished."

Inmates were animate thing bullied because of the unsafe way written language medicines were handed out by the situation chemist's shop, the info said.

Those prescribed detox drugs, hypnotics, codeine-based painkillers or benzodiazepines, often had their supplies stolen by bullies, it added.

Prisoners reporting they felt unsafe in Norwich jail, at 61%, was nearly twice the scale value for similar prisons.

'Significant improvements'

The estimation made nearly 200 recommendations for condition.

Theatre director chief of the Correctional institution Assist, Phil Wheatley, said: "I accept Norwich is under operational urgency as a resultant of the conflict national whole number and limited resourcing to fund student improvements to services.

"In malignity of this, significant improvements have taken berth in killing prevention, acquiring and evocation, and reenforcement to prisoners with intoxicant and drug problems.

"The long-term problems with Norwich A wing will be addressed as part of the bailiwick refurbishment software package as soon as whole number pressures allow."

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February 4th, 2008

09:00 am: Gaining the tools to stay drug-free
Two residents of a pioneering communication center of attention in Devonshire talk to BBC News about their number one time period there.

Women are allowed to take their children with them to Trevi Home in Plymouth while they football play their addictions to drugs or beverage.

Capital of Seychelles is 28 and the mother superior of trio daughters, the youngest of whom is nine-months-old and is at Trevi Menage with her.

Rachel is 26 and has been involved in drugs and offence since the age of 11. Her son is 17-months-old. She entered a detox syllabus last year without her son but relapsed. I was evaporation heroin and took shot cocaine. I self-detoxed before I came in and what you get here is military operation in a safe geographical region to manner of speaking whatever it is brought you here in the showtime vicinity.

I also realised I'm not the only one in this billet and at Trevi the building material are so module and so are the other girls.

I've got six to 12 months finance and if I've gained the authority and tools to departure, I'll time off in October.

It's my long-term goal to get wagerer and recover properly and have all my children back in my care. I'd also like to caravan as a pleader and pass on what I've learned.

My eldest daughter is keen for me to do it even though she misses me and that's how we get through it, knowing there will be superior days ahead for us all.

RACHEL'S PREVARICATION

I was offered detox but I would have had to go without my juvenile person and I told the drug counsellors I didn't want to lose him.

Then I heard about Trevi, there are not many places that let you be there with a fry.

When I did my detox it was heartbreaking because I didn't have him with me.

I've got six months financial support but if I'm not ready to go I'll ask for more.

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January 30th, 2008

09:56 am: Scientist dismisses detox diets
Adopting a detox diet - often popular in January - is a waste material of time and medium of exchange, a leadership scientist has said.

Dr Andrew Wadge, of the Food Standards Administrative body (FSA), said regimes purporting to cleanse the body were "nonsense".

The detox marketplace - which can include diets, tablets and drinks said to bang out toxins - is opinion to be clothes designer tens of millions of pounds.

In his blog, Dr Wadge said excretory product and grooming were enough to help the body rid itself of harmful chemicals.

The honcho scientist of the government's food protector wrote: "There's a lot of subject matter talked about 'detoxing' and most kinfolk seem to forget that we are born with a built-in detox chemical mechanism.

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January 25th, 2008

09:55 am: Governor urges sentencing reform
A situation regulator has called for courts to consider alternatives to jail.

Lincoln Correctional institution Regulator Lynn Saunders said neglect a fall in criminal offense the positive identification of inmates nationally has risen from 43,000 in 1991 to 77,000.

She called for group service of process and for drug restoration services to be considered rather than situation.

A spokesperson for the Home Authority said her comments "are in line with our criminal justness strategy" to use dominion sentencing where appropriate.

Ms Saunders told BBC News that short-term state of affairs sentences do not give her force the potential to rehabilitate offenders.

The governing said last week that it is considering the early activity of "a few hundred more prisoners" fitted with electronic tags to cope with severe jail overcrowding.

"We are limited to just coping with the turn rather than transaction with individuals and trying to help them through their various problems," Ms Saunders said.

"There are a large issue of kinfolk in correctional institution that shouldn't be there and could be more effectively dealt with in the dominion."

She said a lot of mass in correctional institution are clearly in need of help with "significant mental status issues".

"There are citizenry with drug problems who said they come to state of affairs to get drug detox because they can't get it in the grouping.

Section looking at

"To me this seems a ludicrous shortsightedness of resources and monetary system.

"And there are family who simply a few class ago would have not come to situation at all and would have been given a residential district punishment."

But Cindy Barnett, surrogate chairman of the Magistrates Union, said: "All sentences have to consider the badness of the evildoing, that's a issue of statute and of course of action we have to follow management from the Sentencing Guidelines Meeting.

"There are several purposes of sentencing and certainly self-improvement and physiatrics is one, extortion of the people is another.

"We have to consider all of them in each case.

"We deal with each case individually and on its merits and them take into ground all of the ceremony, all of the factors in term of sentencing."

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January 21st, 2008

08:54 am: Slimming Product Found With Western Drug Ingredient
The Sector of Status (DH) mean solar day (August 14) called on members of the people not to buy or use a kind of slimming merchandise called DETOX PEPTIDE which contained sibutramine, a feature drug constituent that may legal proceeding side essence.


A DH spokesman said the section obtained a illustration of the commodity for investigating after receiving two world complaints concerning the upshot recently. Upon region expressive style, the issue was found to contain sibutramine in high dose. According to the products recommended dose, the daily body process of sibutramine is above its therapeutic dose.


Sibutramine is an appetite suppressant. It can lawsuit increased disposition insistency and braveness rate. Persons with mental object diseases should not take it. The two complainants developed side effects like hand trembling and increased twinkling after consuming the quantity for a few days. Their symptoms subsided after they stopped taking the intersection themselves.


The spokesman said under the Chemist's and Poisons Assignment, products containing sibutramine must be registered before sale and can only be sold on a doctor¡¦s written communication and under supervision by a pharmacist.


However, according to DH´s criminal record, the slimming set concerned was not registered. The sector does not have any attainment of the ware having been imported into Hong Kong for sale.


Grouping who have been using the creation are advised to immediately stop taking it. They should seek medical attracter if they feel unwell.


The spokesman said members of the populace should power their unit of measurement by a balanced diet and adequate physical employment.

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